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Reduced Susceptibility to Neuraminidase Inhibitors in Influenza B Isolate, Canada

We identified an influenza B isolate harboring a Gly407Ser neuraminidase substitution in an immunocompromised patient in Canada before antiviral therapy. This mutation mediated reduced susceptibility to oseltamivir, zanamivir, and peramivir, most likely by preventing interaction with the catalytic A...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Emerg Infect Dis
Prif Awduron: Abed, Yacine, Fage, Clément, Lagüe, Patrick, Carbonneau, Julie, Papenburg, Jesse, Vinh, Donald C., Boivin, Guy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Centers for Disease Control and Prevention 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433030/
https://ncbi.nlm.nih.gov/pubmed/30882323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid2504.181554
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