HLA-DRB1 reduces the risk of type 2 diabetes mellitus by increased insulin secretion

AIMS/HYPOTHESIS: We sought to identify the physiological implications of genetic variation at the HLA-DRB1 region in full-heritage Pima Indians in Arizona. METHODS: Single-nucleotide polymorphisms from the HLA region on chromosome 6p were tested for association with skeletal muscle mRNA expression o...

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Gepubliceerd in:Diabetologia
Hoofdauteurs: Williams, R. C., Muller, Y. L., Hanson, R. L., Knowler, W. C., Mason, C. C., Bian, L., Ossowski, V., Wiedrich, K., Chen, Y. F., Marcovina, S., Hahnke, J., Nelson, R. G., Baier, L. J., Bogardus, C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432927/
https://ncbi.nlm.nih.gov/pubmed/21484216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2122-8
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