Lataa...
Design, synthesis and biological evaluation of novel indolin-2-ones as potent anticancer compounds
The indolin-2-one core is a privileged structure for antitumor agents, especially kinase inhibitors. Twenty-three novel indolin-2-ones were designed by molecular dissection of the anticancer drug indirubin. Seventeen of them exhibited significant inhibition against the tested cell lines, and two of...
Tallennettuna:
| Julkaisussa: | Bioorg Med Chem Lett |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2017
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6432916/ https://ncbi.nlm.nih.gov/pubmed/28625363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2017.06.019 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|