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Glucocorticoid Receptor-Deficient Foxp3(+) Regulatory T Cells Fail to Control Experimental Inflammatory Bowel Disease

Activation of the immune system increases systemic adrenal-derived glucocorticoid (GC) levels which downregulate the immune response as part of a negative feedback loop. While CD4(+) T cells are essential target cells affected by GC, it is not known whether these hormones exert their major effects o...

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Bibliografiset tiedot
Julkaisussa:Front Immunol
Päätekijät: Rocamora-Reverte, Lourdes, Tuzlak, Selma, von Raffay, Laura, Tisch, Marcel, Fiegl, Heidi, Drach, Mathias, Reichardt, Holger M., Villunger, Andreas, Tischner, Denise, Wiegers, G. Jan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431616/
https://ncbi.nlm.nih.gov/pubmed/30936873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00472
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