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Mutual antagonism of TGF-beta and Interleukin-2 in cell survival and lineage commitment of induced regulatory T cells

Transforming growth factor beta (TGF-β)- and Interleukin-2 (IL-2)-mediated signaling enables the generation and expansion of induced regulatory T (iTreg) cells that carry high hopes for the treatment of chronic inflammatory and autoimmune diseases. Knowledge about factors stabilizing their lineage c...

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Bibliografski detalji
Glavni autori: Tischner, D, Wiegers, G J, Fiegl, H, Drach, M, Villunger, A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392638/
https://ncbi.nlm.nih.gov/pubmed/22322859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.7
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