The AHR regulates metabolic reprogramming to promote SIRT1-dependent keratinocyte differentiation

Activation of the transcription factor, the aryl hydrocarbon receptor (AHR), in normal human epidermal keratinocytes (NHEKs) increased AHR binding in the promoters of the glucose transporter, SLC2A1, and the glycolytic enzyme, enolase 1 (ENO1). This increased chromatin binding corresponded with AHR-...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Invest Dermatol
Huvudupphovsmän: Sutter, Carrie Hayes, Olesen, Kristin M., Bhuju, Jyoti, Guo, Zibiao, Sutter, Thomas R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431567/
https://ncbi.nlm.nih.gov/pubmed/30393078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2018.10.019
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk