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The AHR regulates metabolic reprogramming to promote SIRT1-dependent keratinocyte differentiation
Activation of the transcription factor, the aryl hydrocarbon receptor (AHR), in normal human epidermal keratinocytes (NHEKs) increased AHR binding in the promoters of the glucose transporter, SLC2A1, and the glycolytic enzyme, enolase 1 (ENO1). This increased chromatin binding corresponded with AHR-...
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| Publicado no: | J Invest Dermatol |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6431567/ https://ncbi.nlm.nih.gov/pubmed/30393078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2018.10.019 |
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