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Treatment of Myotonia Congenita with Retigabine in Mice
Patients with myotonia congenita suffer from muscle stiffness caused by muscle hyperexcitability. Although loss-of-function mutations in the ClC-1 muscle chloride channel have been known for 25 years to cause myotonia congenita, this discovery has led to little progress on development of therapy. Cu...
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| Vydáno v: | Exp Neurol |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6431423/ https://ncbi.nlm.nih.gov/pubmed/30738808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.02.002 |
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