Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis

The BCL6 Corepressor (BCOR) is a component of a variant Polycomb repressive complex 1 (PRC1) that is essential for normal development. Recurrent mutations in the BCOR gene have been identified in acute myeloid leukaemia and myelodysplastic syndrome among other cancers; however, its function remains...

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Vydáno v:Nat Commun
Hlavní autoři: Kelly, Madison J., So, Joan, Rogers, Amy J., Gregory, Gareth, Li, Jason, Zethoven, Magnus, Gearhart, Micah D., Bardwell, Vivian J., Johnstone, Ricky W., Vervoort, Stephin J., Kats, Lev M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430802/
https://ncbi.nlm.nih.gov/pubmed/30902969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09250-6
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