BCOR regulates myeloid cell proliferation and differentiation

BCOR is a component of a variant Polycomb group repressive complex 1 (PRC1). Recently, we and others reported recurrent somatic BCOR loss-of-function mutations in myelodysplastic syndrome and acute myelogenous leukaemia (AML). However, the role of BCOR in normal hematopoiesis is largely unknown. Her...

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Pubblicato in:Leukemia
Autori principali: Cao, Qi, Gearhart, Micah D., Gery, Sigal, Shojaee, Seyedmehdi, Yang, Henry, Sun, Haibo, Lin, De-chen, Bai, Jing-wen, Mead, Monica, Zhao, Zhiqiang, Chen, Qi, Chien, Wen-wen, Alkan, Serhan, Alpermann, Tamara, Haferlach, Torsten, Müschen, Markus, Bardwell, Vivian J., Koeffler, H. Phillip
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131645/
https://ncbi.nlm.nih.gov/pubmed/26847029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.2
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