Ubiquitination of MAP1LC3B by pVHL is associated with autophagy and cell death in renal cell carcinoma

Von Hippel Lindau (VHL) expression is significantly decreased in high-grade RCC, and autophagy, which is involved in tumor growth, invasion, differentiation, and metastasis, is activated in various human cancers. However, the relationship of autophagy and VHL in tumor progression remains controversi...

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Publicat a:Cell Death Dis
Autors principals: Kang, Hyun Mi, Noh, Kyung Hee, Chang, Tae Kyung, Park, Dongmin, Cho, Hyun-Soo, Lim, Jung Hwa, Jung, Cho-Rok
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430800/
https://ncbi.nlm.nih.gov/pubmed/30902965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1520-6
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