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Tissue-type plasminogen activator neutralizes LPS but not protease-activated receptor-mediated inflammatory responses to plasmin
Tissue-type plasminogen activator (tPA) activates fibrinolysis and also suppresses innate immune system responses to lipopolysaccharide (LPS) in bone marrow-derived macrophages (BMDMs) and in vivo in mice. The objective of this study was to assess the activity of tPA as a regulator of macrophage phy...
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| Udgivet i: | J Leukoc Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6430673/ https://ncbi.nlm.nih.gov/pubmed/30690783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3A0818-329RRR |
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