A chemoproteomic portrait of the oncometabolite fumarate

Hereditary cancer disorders often provide an important window into novel mechanisms supporting tumor growth. Understanding these mechanisms thus represents a vital goal. Towards this goal, here we report a chemoproteomic map of fumarate, a covalent oncometabolite whose accumulation marks the genetic...

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Bibliografische gegevens
Gepubliceerd in:Nat Chem Biol
Hoofdauteurs: Kulkarni, Rhushikesh A., Bak, Daniel W., Wei, Darmood, Bergholtz, Sarah E., Briney, Chloe A., Shrimp, Jonathan H., Alpsoy, Aktan, Thorpe, Abigail L., Bavari, Arissa E., Crooks, Daniel R., Levy, Michaella, Florens, Laurence, Washburn, Michael P., Frizzell, Norma, Dykhuizen, Emily C., Weerapana, Eranthie, Linehan, W. Marston, Meier, Jordan L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430658/
https://ncbi.nlm.nih.gov/pubmed/30718813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0217-y
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