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Co-opting a bioorthogonal reaction for oncometabolite detection

Dysregulated metabolism is a hallmark of many diseases, including cancer. Methods to fluorescently detect metabolites have the potential to enable new approaches to cancer detection and imaging. However, fluorescent sensing methods for naturally occurring cellular metabolites are relatively unexplor...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Principais autores: Zengeya, Thomas T., Garlick, Julie M., Kulkarni, Rhushikesh A., Miley, Mikayla, Roberts, Allison M., Yang, Youfeng, Crooks, Daniel R., Sourbier, Carole, Linehan, W. Marston, Meier, Jordan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377280/
https://ncbi.nlm.nih.gov/pubmed/27960310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b09706
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