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Co-opting a bioorthogonal reaction for oncometabolite detection

Dysregulated metabolism is a hallmark of many diseases, including cancer. Methods to fluorescently detect metabolites have the potential to enable new approaches to cancer detection and imaging. However, fluorescent sensing methods for naturally occurring cellular metabolites are relatively unexplor...

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Dettagli Bibliografici
Pubblicato in:J Am Chem Soc
Autori principali: Zengeya, Thomas T., Garlick, Julie M., Kulkarni, Rhushikesh A., Miley, Mikayla, Roberts, Allison M., Yang, Youfeng, Crooks, Daniel R., Sourbier, Carole, Linehan, W. Marston, Meier, Jordan L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377280/
https://ncbi.nlm.nih.gov/pubmed/27960310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b09706
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