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Residues on Adeno-associated Virus Capsid Lumen Dictate Interactions and Compatibility with the Assembly-Activating Protein

The adeno-associated virus (AAV) serves as a broadly used vector system for in vivo gene delivery. The process of AAV capsid assembly remains poorly understood. The viral cofactor assembly-activating protein (AAP) is required for maximum AAV production and has multiple roles in capsid assembly, name...

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Bibliographic Details
Published in:J Virol
Main Authors: Maurer, Anna C., Cepeda Diaz, Ana Karla, Vandenberghe, Luk H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430561/
https://ncbi.nlm.nih.gov/pubmed/30651367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02013-18
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