The pharmacological properties of 3-arm or 4-arm DOTA constructs for conjugation to α-melanocyte-stimulating hormone analogues for melanoma imaging

BACKGROUND: Although a 3-arm DOTA construct, which has three carboxylic acids, h has been applied for conjugation to many peptides, we investigated if a 4-arm DOTA construct conjugated to peptides improves chemical properties for melanoma imaging of the melanocortin 1 receptor compared to 3-arm DOTA...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kobayashi, Masato, Kato, Toshitaka, Washiyama, Kohshin, Ihara, Masaaki, Mizutani, Asuka, Nishi, Kodai, Flores, Leo G., Nishii, Ryuichi, Kawai, Keiichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430397/
https://ncbi.nlm.nih.gov/pubmed/30901323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213397
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