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Imaging of hepatic drug transporters with [(131)I]6-β-iodomethyl-19-norcholesterol
We examined whether [(131)I]6-β-iodomethyl-19-norcholesterol (NP-59), a cholesterol analog, can be used to measure function of hepatic drug transporters. Hepatic uptake of NP-59 with and without rifampicin was evaluated using HEK293 cells expressing solute carrier transporters. The stability of NP-5...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6746803/ https://ncbi.nlm.nih.gov/pubmed/31527775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50049-8 |
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