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Interpreting Hydrogen-Deuterium Exchange Events in Proteins Using Atomistic Simulations: Case Studies on Regulators of G-protein Signaling Proteins

Hydrogen-deuterium exchange (HDX) experiments are widely used in studies of protein dynamics. To predict the propensity of amide-hydrogens for exchange with deuterium, several models have been reported in which computations of amide-hydrogen protection factors are carried out using molecular dynamic...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Mohammadiarani, Hossein, Shaw, Vincent S., Neubig, Richard R., Vashisth, Harish
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430106/
https://ncbi.nlm.nih.gov/pubmed/30222348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b07494
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