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Three different polymorphisms of the DPYD gene associated with severe toxicity following administration of 5-FU: a case report
BACKGROUND: Dihydropyrimidine dehydrogenase deficiency secondary to polymorphisms in the DPYD gene can lead to significant toxicity associated with the administration of fluoropyrimidine chemotherapy. CASE PRESENTATION: We report a case of a 59-year-old Lebanese woman with metastatic pancreatic canc...
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| Vydáno v: | J Med Case Rep |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6429833/ https://ncbi.nlm.nih.gov/pubmed/30898145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13256-019-2013-z |
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