Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease is a progressive neurodegenerative disorder that is hypothesized to involve epigenetic dysfunction. Previous studies of DNA modifications in Alzheimer’s disease have been unable to distinguish between DNA methylation and DNA hydroxymethylation. DNA hydroxymethylation...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Epigenetics
Päätekijät: Smith, Adam R., Smith, Rebecca G., Pishva, Ehsan, Hannon, Eilis, Roubroeks, Janou A. Y., Burrage, Joe, Troakes, Claire, Al-Sarraj, Safa, Sloan, Carolyn, Mill, Jonathan, van den Hove, Daniel L., Lunnon, Katie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2019
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429761/
https://ncbi.nlm.nih.gov/pubmed/30898171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0636-y
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