Sirtuins in Alzheimer’s Disease: SIRT2-Related GenoPhenotypes and Implications for PharmacoEpiGenetics

Sirtuins (SIRT1-7) are NAD(+)-dependent protein deacetylases/ADP ribosyltransferases with important roles in chromatin silencing, cell cycle regulation, cellular differentiation, cellular stress response, metabolism and aging. Sirtuins are components of the epigenetic machinery, which is disturbed i...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Cacabelos, Ramón, Carril, Juan C., Cacabelos, Natalia, Kazantsev, Aleksey G., Vostrov, Alex V., Corzo, Lola, Cacabelos, Pablo, Goldgaber, Dmitry
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429449/
https://ncbi.nlm.nih.gov/pubmed/30871086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051249
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