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Sirtuins in Alzheimer’s Disease: SIRT2-Related GenoPhenotypes and Implications for PharmacoEpiGenetics
Sirtuins (SIRT1-7) are NAD(+)-dependent protein deacetylases/ADP ribosyltransferases with important roles in chromatin silencing, cell cycle regulation, cellular differentiation, cellular stress response, metabolism and aging. Sirtuins are components of the epigenetic machinery, which is disturbed i...
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| Gepubliceerd in: | Int J Mol Sci |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
MDPI
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6429449/ https://ncbi.nlm.nih.gov/pubmed/30871086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051249 |
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