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Synthesis and Antitumor Activity of a Series of Novel 1-Oxa-4-azaspiro[4,5]deca-6,9-diene-3,8-dione Derivatives

A series of novel 1-oxa-4-azaspiro[4.5]deca-6,9-diene-3,8-diones were designed and synthesized by using 4-aminophenol and α-glycolic acid or lactic acid as starting materials in three or four steps. The key step is the metal-catalyzed oxidative cyclization of the amide to 1-oxa-4-azaspiro[4.5]deca-6...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Yang, Ze, Zhong, Qiu, Zheng, Shilong, Wang, Guangdi, He, Ling
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429447/
https://ncbi.nlm.nih.gov/pubmed/30866506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24050936
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