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Strong Inhibition of Cholera Toxin B Subunit by Affordable, Polymer-Based Multivalent Inhibitors

[Image: see text] Cholera is a potentially fatal bacterial infection that affects a large number of people in developing countries. It is caused by the cholera toxin (CT), an AB(5) toxin secreted by Vibrio cholera. The toxin comprises a toxic A-subunit and a pentameric B-subunit that bind to the int...

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Detalles Bibliográficos
Publicado en:Bioconjug Chem
Main Authors: Haksar, Diksha, de Poel, Eyleen, van Ufford, Linda Quarles, Bhatia, Sumati, Haag, Rainer, Beekman, Jeffrey, Pieters, Roland J.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2019
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429436/
https://ncbi.nlm.nih.gov/pubmed/30629410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00902
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