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Exploring monovalent and multivalent peptides for the inhibition of FBP21-tWW

The coupling of peptides to polyglycerol carriers represents an important route towards the multivalent display of protein ligands. In particular, the inhibition of low affinity intracellular protein–protein interactions can be addressed by this design. We have applied this strategy to develop bindi...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Henning, Lisa Maria, Bhatia, Sumati, Bertazzon, Miriam, Marczynke, Michaela, Seitz, Oliver, Volkmer, Rudolf, Haag, Rainer, Freund, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464085/
https://ncbi.nlm.nih.gov/pubmed/26124874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.80
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