Structure and Function of the Two Tandem WW Domains of the Pre-mRNA Splicing Factor FBP21 (Formin-binding Protein 21)

Human FBP21 (formin-binding protein 21) contains a matrin-type zinc finger and two tandem WW domains. It is a component of the spliceosomes and interacts with several established splicing factors. Here we demonstrate for the first time that FBP21 is an activator of pre-mRNA splicing in vivo and that...

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Main Authors: Huang, Xiaojuan, Beullens, Monique, Zhang, Jiahai, Zhou, Yi, Nicolaescu, Emilia, Lesage, Bart, Hu, Qi, Wu, Jihui, Bollen, Mathieu, Shi, Yunyu
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757239/
https://ncbi.nlm.nih.gov/pubmed/19592703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.024828
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