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Multivalent Binding of Formin-binding Protein 21 (FBP21)-Tandem-WW Domains Fosters Protein Recognition in the Pre-spliceosome

The high abundance of repetitive but nonidentical proline-rich sequences in spliceosomal proteins raises the question of how these known interaction motifs recruit their interacting protein domains. Whereas complex formation of these adaptors with individual motifs has been studied in great detail,...

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Detalhes bibliográficos
Main Authors: Klippel, Stefan, Wieczorek, Marek, Schümann, Michael, Krause, Eberhard, Marg, Berenice, Seidel, Thorsten, Meyer, Tim, Knapp, Ernst-Walter, Freund, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207436/
https://ncbi.nlm.nih.gov/pubmed/21917930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.265710
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