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Hetero-multivalent Binding of Cholera Toxin Subunit B with Glycolipid Mixtures

GM(1) has generally been considered as the major receptor that binds to cholera toxin subunit B (CTB) due to its low dissociation constant. However, using a unique nanocube sensor technology, we have shown that CTB can also bind to other glycolipid receptors, fucosyl-GM(1) and GD(1)b. Additionally,...

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Detalhes bibliográficos
Publicado no:Colloids Surf B Biointerfaces
Main Authors: Krishnan, Pratik, Singla, Akshi, Lee, Chin-An, Weatherston, Joshua D., Worstell, Nolan C., Wu, Hung-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714677/
https://ncbi.nlm.nih.gov/pubmed/28946063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.colsurfb.2017.09.035
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