Immobilization of Denosumab on Titanium Affects Osteoclastogenesis of Human Peripheral Blood Monocytes

Immobilization of proteins has been examined to improve implant surfaces. In this study, titanium surfaces were modified with nanofunctionalized denosumab (cDMAB), a human monoclonal anti-RANKL IgG. Noncoding DNA oligonucleotides (ODN) served as linker molecules between titanium and DMAB. Binding an...

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Publicado en:Int J Mol Sci
Autores principales: Beck, Felicitas, Hartmann, Eliza S., Koehler, Miriam I., Redeker, Julia I., Schluessel, Sabine, Schmitt, Baerbel, Fottner, Andreas, Unger, Marina, van Griensven, Martijn, Michael, Jan, Summer, Burkhard, Kunzelmann, Karl-Heinz, Beutner, Rene, Scharnweber, Dieter, Kostenuik, Paul J., Mayer-Wagner, Susanne
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429431/
https://ncbi.nlm.nih.gov/pubmed/30813507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051002
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