Immobilization of Denosumab on Titanium Affects Osteoclastogenesis of Human Peripheral Blood Monocytes

Immobilization of proteins has been examined to improve implant surfaces. In this study, titanium surfaces were modified with nanofunctionalized denosumab (cDMAB), a human monoclonal anti-RANKL IgG. Noncoding DNA oligonucleotides (ODN) served as linker molecules between titanium and DMAB. Binding an...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Beck, Felicitas, Hartmann, Eliza S., Koehler, Miriam I., Redeker, Julia I., Schluessel, Sabine, Schmitt, Baerbel, Fottner, Andreas, Unger, Marina, van Griensven, Martijn, Michael, Jan, Summer, Burkhard, Kunzelmann, Karl-Heinz, Beutner, Rene, Scharnweber, Dieter, Kostenuik, Paul J., Mayer-Wagner, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429431/
https://ncbi.nlm.nih.gov/pubmed/30813507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051002
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