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Immobilization of Denosumab on Titanium Affects Osteoclastogenesis of Human Peripheral Blood Monocytes

Immobilization of proteins has been examined to improve implant surfaces. In this study, titanium surfaces were modified with nanofunctionalized denosumab (cDMAB), a human monoclonal anti-RANKL IgG. Noncoding DNA oligonucleotides (ODN) served as linker molecules between titanium and DMAB. Binding an...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Beck, Felicitas, Hartmann, Eliza S., Koehler, Miriam I., Redeker, Julia I., Schluessel, Sabine, Schmitt, Baerbel, Fottner, Andreas, Unger, Marina, van Griensven, Martijn, Michael, Jan, Summer, Burkhard, Kunzelmann, Karl-Heinz, Beutner, Rene, Scharnweber, Dieter, Kostenuik, Paul J., Mayer-Wagner, Susanne
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429431/
https://ncbi.nlm.nih.gov/pubmed/30813507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051002
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