Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphoma

Although generally curable with intensive chemotherapy in resource-rich settings, Burkitt lymphoma (BL) remains a deadly disease in older patients and in sub-Saharan Africa. Epstein-Barr virus (EBV) positivity is a feature in more than 90% of cases in malaria-endemic regions, and up to 30% elsewhere...

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Published in:Blood
Main Authors: Grande, Bruno M., Gerhard, Daniela S., Jiang, Aixiang, Griner, Nicholas B., Abramson, Jeremy S., Alexander, Thomas B., Allen, Hilary, Ayers, Leona W., Bethony, Jeffrey M., Bhatia, Kishor, Bowen, Jay, Casper, Corey, Choi, John Kim, Culibrk, Luka, Davidsen, Tanja M., Dyer, Maureen A., Gastier-Foster, Julie M., Gesuwan, Patee, Greiner, Timothy C., Gross, Thomas G., Hanf, Benjamin, Harris, Nancy Lee, He, Yiwen, Irvin, John D., Jaffe, Elaine S., Jones, Steven J. M., Kerchan, Patrick, Knoetze, Nicole, Leal, Fabio E., Lichtenberg, Tara M., Ma, Yussanne, Martin, Jean Paul, Martin, Marie-Reine, Mbulaiteye, Sam M., Mullighan, Charles G., Mungall, Andrew J., Namirembe, Constance, Novik, Karen, Noy, Ariela, Ogwang, Martin D., Omoding, Abraham, Orem, Jackson, Reynolds, Steven J., Rushton, Christopher K., Sandlund, John T., Schmitz, Roland, Taylor, Cynthia, Wilson, Wyndham H., Wright, George W., Zhao, Eric Y., Marra, Marco A., Morin, Ryan D., Staudt, Louis M.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2019
Subjects:
Lymphoid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428665/
https://ncbi.nlm.nih.gov/pubmed/30617194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-09-871418
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