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Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade-specific epigenome and transcriptome landscapes.

Cervical cancer is the most common cancer affecting sub-Saharan African women and is prevalent among HIV positive (HIV+) patients. No comprehensive profiling of cancer genomes, transcriptomes or epigenomes has been performed in this population to date. We characterized 118 tumors from Ugandan patien...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Gagliardi, Alessia, Porter, Vanessa L., Zong, Zusheng, Bowlby, Reanne, Titmuss, Emma, Namirembe, Constance, Griner, Nicholas B., Petrello, Hilary, Bowen, Jay, Chan, Simon K., Culibrk, Luka, Darragh, Teresa M., Stoler, Mark H., Wright, Thomas C., Gesuwan, Patee, Dyer, Maureen A., Ma, Yussanne, Mungall, Karen L., Jones, Steven J.M., Nakisige, Carolyn, Novik, Karen, Orem, Jackson, Origa, Martin, Gastier-Foster, Julie M., Yarchoan, Robert, Casper, Corey, Mills, Gordon B., Rader, Janet S., Ojesina, Akinyemi I., Gerhard, Daniela S., Mungall, Andrew J., Marra, Marco A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498180/
https://ncbi.nlm.nih.gov/pubmed/32747824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-0673-7
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