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Development of rectal enema as microbicide (DREAM): Preclinical progressive selection of a tenofovir prodrug enema

HIV pre-exposure prophylaxis (PrEP) strategies have the potential to prevent millions of incident HIV infections each year. However, the efficacy of PrEP strategies has been plagued by issues of non-adherence, likely because of the difficulty in motivating otherwise healthy people to adhere to treat...

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Détails bibliographiques
Publié dans:Eur J Pharm Biopharm
Auteurs principaux: Hoang, Thuy, Date, Abhijit A., Ortiz, Jairo Ortiz, Young, Ting-Wei, Bensouda, Sabrine, Xiao, Peng, Marzinke, Mark, Rohan, Lisa, Fuchs, Edward J., Hendrix, Craig, Gumber, Sanjeev, Villinger, Francois, Cone, Richard A., Hanes, Justin, Ensign, Laura M.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428633/
https://ncbi.nlm.nih.gov/pubmed/29802984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2018.05.030
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