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IRBIT is a novel regulator of ribonucleotide reductase in higher eukaryotes

Ribonucleotide reductase (RNR) supplies the balanced pools of deoxynucleotide triphosphates (dNTPs) necessary for DNA replication and maintenance of genomic integrity. RNR is subject to allosteric regulatory mechanisms in all eukaryotes, as well as to control by small protein inhibitors Sml1p and Sp...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Science
Prif Awduron: Arnaoutov, Alexei, Dasso, Mary
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428578/
https://ncbi.nlm.nih.gov/pubmed/25237103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1251550
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