Activation of the mTOR/ Akt pathway in thymic epithelial cells derived from thymomas

The pathogenesis of thymic epithelial tumors remains poorly elucidated. The PIK3/Akt/mTOR pathway plays a key role in various cancers; interestingly, several phase I/II studies have reported a positive effect of mTOR inhibitors in disease control in thymoma patients. A major limit for deciphering ce...

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Опубликовано в: :PLoS One
Главные авторы: Maury, Jean-Michel, Merveilleux du Vignaux, Claire, Drevet, Gabrielle, Zarza, Virginie, Chalabreysse, Lara, Maisse, Carine, Gineys, Barbara, Dolmazon, Christine, Tronc, François, Girard, Nicolas, Leroux, Caroline
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428316/
https://ncbi.nlm.nih.gov/pubmed/30897085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197655
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