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Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides

Interleukin-1β (IL-1β) is a major cytokine that initiates and enhances inflammatory responses. Excessive IL-1β production is a characteristic of most chronic inflammatory diseases, including atherosclerosis, type 2 diabetes, and obesity, which affect a large proportion of the global population. The...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Pal, Arumay, Neo, Kurt, Rajamani, Lakshminarayanan, Ferrer, Fernando Jose, Lane, David P., Verma, Chandra S., Mortellaro, Alessandra
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426897/
https://ncbi.nlm.nih.gov/pubmed/30894604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41211-3
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