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Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex
The question vis-à-vis the chemistry of phosphoryl group transfer catalyzed by protein kinases remains a major challenge. The neutron diffraction structure of the catalytic subunit of cAMP-dependent protein kinase (PKA-C) provides a more complete chemical portrait of key proton interactions at the a...
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| 發表在: | Sci Adv |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Association for the Advancement of Science
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6426457/ https://ncbi.nlm.nih.gov/pubmed/30906862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav0482 |
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