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Synthesis and evaluation of verticipyrone analogues as mitochondrial complex I inhibitors
Verticipyrone has recently been isolated from the culture broth of Verticillium sp. and shown to inhibit NADH fumarate reductase, as well as NADH oxidoreductase (complex I) of the mitochondrial electron transport chain. In order to assess the structural elements in verticipyrone essential for comple...
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| Publicado no: | Bioorg Med Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6426446/ https://ncbi.nlm.nih.gov/pubmed/20456960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.03.070 |
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