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Chemical synthesis of lipophilic methylene blue analogues which increase mitochondrial biogenesis and frataxin levels

As part of an ongoing program to develop potential therapeutic agents for the treatment of the neurodegenerative disease Friedreich׳s ataxia (FRDA), we have prepared a number of lipophilic methylene blue analogues. Some of these compounds significantly increase mitochondrial biogenesis and frataxin...

詳細記述

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書誌詳細
出版年:Data Brief
主要な著者: Bandyopadhyay, Indrajit, Chowdhury, Sandipan Roy, Visavadiya, Nishant P., Hecht, Sidney M., Khdour, Omar M.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139889/
https://ncbi.nlm.nih.gov/pubmed/30225325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dib.2018.08.156
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