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Exact confidence limits for the probability of response in two-stage designs

In addition to point estimate for the probability of response in a two-stage design (e.g., Simon’s two-stage design for a Phase II clinical trial with binary endpoints), confidence limits should be Cute the confidence interval does not guarantee coverage probability in a two-stage setting. The exist...

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Publicat a:Statistics (Ber)
Autor principal: Shan, Guogen
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426334/
https://ncbi.nlm.nih.gov/pubmed/30906095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02331888.2018.1469023
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