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When size matters: transient receptor potential vanilloid 4 channel as a volume‐sensor rather than an osmo‐sensor
KEY POINTS: Mammalian cells are frequently exposed to stressors causing volume changes. The transient receptor potential vanilloid 4 (TRPV4) channel translates osmotic stress into ion flux. The molecular mechanism coupling osmolarity to TRPV4 activation remains elusive. TRPV4 responds to isosmolar c...
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| Publicado no: | J Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6426160/ https://ncbi.nlm.nih.gov/pubmed/28295351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274135 |
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