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Volume sensing in the transient receptor potential vanilloid 4 ion channel is cell type–specific and mediated by an N-terminal volume-sensing domain

Many retinal diseases are associated with pathological cell swelling, but the underlying etiology remains to be established. A key component of the volume-sensitive machinery, the transient receptor potential vanilloid 4 (TRPV4) ion channel, may represent a sensor and transducer of cell swelling, bu...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Toft-Bertelsen, Trine L., Yarishkin, Oleg, Redmon, Sarah, Phuong, Tam T. T., Križaj, David, MacAulay, Nanna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885641/
https://ncbi.nlm.nih.gov/pubmed/31619514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011187
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