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Sensing and regulation of cell volume – we know so much and yet understand so little: TRPV4 as a sensor of volume changes but possibly without a volume-regulatory role?

Cellular volume changes lead to initiation of cell volume regulatory events, the molecular identity of which remains unresolved. We here discuss experimental challenges associated with investigation of volume regulation during application of large, non-physiological osmotic gradients. The TRPV4 ion...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Main Authors: Toft-Bertelsen, Trine L., Larsen, Brian R., MacAulay, Nanna
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972811/
https://ncbi.nlm.nih.gov/pubmed/29424275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2018.1438009
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