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A Unified Strategy for the Syntheses of the Isoquinolinium Alkaloids Berberine, Coptisine, and Jatrorrhizine
Total syntheses of the antibacterial alkaloids berberine, coptisine, and jatrorrhizine have been achieved in four steps through a unified route. The key step of this strategy is an efficient intramolecular Friedel–Crafts alkoxyalkylation which, following oxidation, establishes the isoquinolinium cor...
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| Udgivet i: | Org Lett |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6426129/ https://ncbi.nlm.nih.gov/pubmed/29952573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b01702 |
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