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Human B Cells Engage the NCK/PI3K/RAC1 Axis to Internalize Large Particles via the IgM-BCR

Growing evidence indicate that large antigen-containing particles induce potent T cell-dependent high-affinity antibody responses. These responses require large particle internalization after recognition by the B cell receptor (BCR) on B cells. However, the molecular mechanisms governing BCR-mediate...

詳細記述

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書誌詳細
出版年:Front Immunol
主要な著者: Verstegen, Niels J. M., Unger, Peter-Paul A., Walker, Julia Z., Nicolet, Benoit P., Jorritsma, Tineke, van Rijssel, Jos, Spaapen, Robbert M., de Wit, Jelle, van Buul, Jaap D., ten Brinke, Anja, van Ham, S. Marieke
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425997/
https://ncbi.nlm.nih.gov/pubmed/30930895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00415
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