Minimalistic In Vitro Culture to Drive Human Naive B Cell Differentiation into Antibody-Secreting Cells

High-affinity antibody-secreting cells (ASC) arise from terminal differentiation of B-cells after coordinated interactions with T follicular helper (Tfh) cells in germinal centers (GC). Elucidation of cues promoting human naive B-cells to progress into ASCs is challenging, as this process is notorio...

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Publicado no:Cells
Main Authors: Unger, Peter-Paul A., Verstegen, Niels J. M., Marsman, Casper, Jorritsma, Tineke, Rispens, Theo, ten Brinke, Anja, van Ham, S. Marieke
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151070/
https://ncbi.nlm.nih.gov/pubmed/34066151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051183
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