Plerixafor for the Treatment of WHIM Syndrome

WHIM syndrome (warts, hypogammaglobulinemia, infections, and myelokathexis), a primary immunodeficiency disorder involving panleukopenia, is caused by autosomal dominant gain-of-function mutations in CXC chemokine receptor 4 (CXCR4). Myelokathexis is neutropenia caused by neutrophil retention in bon...

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Bibliografiske detaljer
Udgivet i:N Engl J Med
Main Authors: McDermott, David H., Pastrana, Diana V., Calvo, Katherine R., Pittaluga, Stefania, Velez, Daniel, Cho, Elena, Liu, Qian, Trout, Hugh H., Neves, João F., Gardner, Pamela J., Bianchi, David A., Blair, Elizabeth A., Landon, Emily M., Silva, Susana L., Buck, Christopher B., Murphy, Philip M.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425947/
https://ncbi.nlm.nih.gov/pubmed/30625055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1808575
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