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Mechanisms of Sustained Neutrophilia in Patient WHIM-09, Cured of WHIM Syndrome by Chromothripsis

WHIM-09 is the first patient described with WHIM syndrome, an autosomal dominant form of neutropenia related to bone marrow retention of neutrophils. Originally diagnosed incorrectly with autoimmune neutropenia, the patient underwent splenectomy at age 9, but the absolute neutrophil count (ANC) did...

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Détails bibliographiques
Publié dans:J Clin Immunol
Auteurs principaux: Liu, Qian, Li, Zhanzhuo, Yang, Alexander, Gao, Ji-Liang, Velez, Daniel, Cho, Elena, McDermott, David H., Murphy, Philip M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743603/
https://ncbi.nlm.nih.gov/pubmed/29177911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-017-0457-8
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